Microorganisms in a Confined Environment – Programmed Research
|Research Subject||A03-3 Microorganisms in a Confined Environment|
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A living environment in Space is a confined environment exposed to cosmic rays under microgravity. To date, experiments in Space have reported the alterations in the pathogenicity of bacteria, such as Salmonella typhimurium and Pseudomonas aeruginosa. Under a simulated microgravity, the stimulation of biofilm formation has been confirmed in bacteria, such as E. coli and Staphylococcus aureus, as well as in a fungus (Candida). On the other hand, a concern has been raised over the decline in the human immunological response in a confined environment due to stress and so on. Therefore, the relationship between humans and microorganisms in Space considerably differ than that on Earth. Hence, to "live in Space" and "to live in comfort on Earth," it is essential to understand the relationship between humans and microorganisms in the confined environment as a model and accumulate knowledge that will be the foundation in order to establish a co-existence of humans and microorganisms.
Our research aims to reduce the microbial risk for a prolonged stay in Space. We will conduct comprehensive analysis of microbiota in a strictly controlled model environment to elucidate their alterations in a confined environment. Additionally, we will advance our research on microbial interactions and their adaptation strategies under microgravity. Based on these results, we plan to examine the microbial risk in a confined environment for a prolonged stay in Space.