A02 : Effects on human organism under higher-order stresses in extreme environments - Publications

Original Articles

  1. 2017
  2. 2016
  3. 2015

2017

  • Essential structure of orexin 1 receptor antagonist YNT-707, Part II: Drastic effect of the 14-hydroxy group on the orexin 1 receptor antagonistic activity, Ohrui S, Yanagisawa M, and Nagase H, et al., Bioorg. Med. Chem. Lett. Volume 28, Issue 4, Pages 774-777, 15 February 2018, doi.org/10.1016/j.bmcl.2017.12.069
  • Acetic Anhydride Mediated Retro-Ene Reaction via a [4.4.3]Propellane Skeleton Intermediate Containing a Quaternary Ammonium Linkage, Kutsumura N and Nagase H, et al., Synthesis, doi:10.1055/s-0036-1589138, (2018)
  • Trial of stress-related index measurement under confinement stress, Y. Oi, Y. Hirai, S. Doki, Y. Ohtaki, D. Hori, C. Andrea, S. Sasahara, T.Saito, I. Matsuzaki: . Transactions of the Japan Society for Aeronautical Space Science, Aerospace Technology Japan, ISTS, Vol.31, 5 pages, 2018
  • The choroid plexus is an important circadian clock component., Myung J, Schmal C, Hong S, Tsukizawa Y, Rose P, Zhang Y, Holtzman MJ, De Schutter E, Herzel H, Bordyugov G, Takumi T, Nature Communications, volume 9, Article number: 1062, Published online:14 March 2018, doi:10.1038/s41467-018-03507-2
  • Non-invasive intracranial pressureestimation during combined exposure to CO2 and head-down tilt., Kurazumi T., Ogawa Y., Yanagida R., Morisaki H., Iwasaki K., Aerosp Med Hum Perform. In Press 2018
  • Roles of irisin in the linkage from muscle to bone during mechanical unloading in mice., Kawao N, Moritake A, Tatsumi K, Kaji H. , Calcif Tissue Int, 2018 Jan 13. doi: 10.1007/s00223-018-0387-3
  • Sleep/wakefulness behaviors in mice during pregnancy and pregnancy-associated hypertensive mice. , Haruna Komiya, Chika Miyoshi, Kanako Iwasaki, Noriko Hotta-Hirashima, Aya Ikkyu, Satomi Kanno, Takato Honda, Masahiko Gosho, Hiromi Hamada, Toyomi Satoh, Akiyoshi Fukamizu, Hiromasa Funato, Masashi Yanagisawa, SLEEP Epub ahead of print.(2018) DOI: 10.1093/sleep/zsx209
  • Activation of endogenous arginine vasopressin neurons inhibit food intake: by using a novel transgenic rat line with DREADDs system., Yoshimura M, Nishimura K, Nishimura H, Sonoda S, Ueno H, Motojima Y,2, Saito R, Maruyama T, Nonaka Y, Ueta Y., Sci Rep, Nov 16;7(1):15728, 2017, doi: 10.1038/s41598-017-16049-2
  • Clinical features of otolith organ-specific vestibular dysfunction. , Fujimoto C, Suzuki S, Kinoshita M, Egami N, Sugasawa K, Iwasaki S. ,Clin Neurophysiol, 129: 238-245, 2018, doi: org/10.1016/j.clinph.2017.11.006.
  • Comparison among ultrasonic, electrical apparatus, and toxic chemicals for vestibular lesion in mice, Yamaoka Y, Abe C, Morita H, Journal of Neuroscience Methods, doi: org/10.1016/j.jneumeth.2017.11.021, 2017.
  • Effects of hypergravity on gene levels in anti-gravity muscle and bone through the vestibular system in mice, Kawao N, Morita H, Nishida K, Obata K, Tatsumi K, Kaji H, Journal of Physiological Sciences, Sep 7. doi: 10.1007/s12576-017-0566-4, 2017
  • Essential structure of orexin 1 receptor antagonist YNT-707, Part I: Role of the 4,5-epoxy ring for binding with orexin 1 receptor, Yamamoto N, Yanagisawa M, Nagase H, et al. Bioorg. Med. Chem. Lett. vol.27, 4176-4179, 2017
  • Neurotransmitters and neuropeptides in gonadal steroid receptor-expressing cells in medial preoptic area subregions of the male mouse, Yousuke Tsuneoka, Sachine Yoshida, Kenkichi Takase, Satoko Oda, Masaru Kuroda, Hiromasa Funato*. Scientific Reports 7: 9809, 1-16, 2017. DOI:10.1038/s41598-017-10213-4
  • Increased oxytocin-monomeric red fluorescent protein 1 fluorescent intensity with urocortin-like immunoreactivity in the hypothalamo-neurohypophysial system of aged transgenic rats., Ohno S, Hashimoto H, Fujihara H, Fujiki N, Yoshimura M, Maruyama T, Motojima Y, Saito R, Ueno H, Sonoda S, Ohno M, Umezu Y, Hamamura A, Saeki S, Ueta Y. Neurosci Res, S0168-0102(17)30164-5, 2017, doi: org/10.1016/j.neures.2017.08.001
  • Arsenic-mediated hyperpigmentation in skin via NF-kappa B/endothelin-1 signaling in an originally developed hairless mouse model, Ichiro Yajima, Mayuko Y. Kumasaka, Machiko Iida, Reina Oshino, Hiroko Tanihata, Aeorangajeb Al Hossain, Nobutaka Ohgami, Masashi Kato, Archives of Toxicology, First Online: 03 May 2017, Volume 91, Issue 11, pp 3507–3516, November 2017 , doi: 10.1007/s00204-017-1975-0
  • Effects of peripheral vestibular dysfunction on dynamic postural stability measured by the functional reach test and timed up and go test. , Nishi T, Kamogashira T, Fujimoto C, Kinoshita M, Egami N, Sugasawa K, Yamasoba T, Iwasaki S. ,Ann Otol Rhinol Laryngol, 126: 438-444, 2017, doi: 10.1177/0003489417700439.
  • Running training experience attenuates disuse atrophy in fast-twitch skeletal muscles of rats, Nakamura K., Ohsawa I., Masuzawa R., Konno R., Watanabe A., and Kawano F, J. Appl. Physiol, 2017 Aug 3:jap.00289.2017. doi: 10.1152/japplphysiol.00289.2017
  • Dynamic Cerebral Autoregulation During the Combination of Mild Hypercapnia and Cephalad Fluid Shift, Kurazumi, Takuya; Ogawa, Yojiro; Yanagida, Ryo; Morisaki, Hiroshi; Iwasaki, Ken-ichi, Aerospace Medicine and Human Performance, Volume 88, Number 9, September 2017, pp. 819-826(8), doi.org/10.3357/AMHP.4870.2017
  • Manganese-Mediated Decrease in Levels of c-RET and Tyrosine Hydroxylase Expression In Vitro, Kumasaka MY, Yajima I, Ohgami N, Ninomiya H, Iida M, Li X, Oshino R, Tanihata H, Yoshinaga M, Kato M, Neurotox Res. 2017 Jul 20, doi:10.1007/s12640-017-9783-0
  • Encoding seasonal information in a two-oscillator model of the multi-oscillator circadian clock, Myung J & Pauls SD, European Journal of Neuroscience, pp. 1-10, 2017, doi:10.1111/ejn.13697
  • Role of follistatin in muscle and bone alterations by gravity change in mice, Kawao N, Morita H, Obata K, Tatsumi K, *Kaji H, Journal of Cellular Physiology, doi:10.1002/jcp.25986, May 4, 2017
  • Impact of a simulated gravity load for atmospheric reentry–10 g for 2 minutes–on conscious mouse. Journal of Physiological Sciences,Morita H, Yamaguchi A, Shiba D, Shirakawa M, Takahashi S , doi:10.1007/s12576-017-0526-z, Feb 9 2017
  • Effect of noisy galvanic vestibular stimulation on ocular vestibular evoked myogenic potentials to bone-conducted vibration., Iwasaki S, Karino S, Kamogashira T, Togo F, Fujimoto C, Yamamoto Y, Yamasoba T.Frontiers in Neurology, 8: 26, doi:10.3389/fneur.2017.00026, 2017
  • Tumour blood vessel normalisation by prolyl hydroxylase inhibitor repaired sensitivity to chemotherapy in a tumour mouse model, Koyama S, Matsunaga S, Imanishi M, Maekawa Y, Kitano H, Takeuchi H, Tomita S,  Scientific Reports, 7:45621. 2017
  • Transmission of survival signals through Delta-like 1 on activated CD4+ T cells, Furukawa T, Ishifune C, Tsukumo S, Hozumi K, Maekawa Y, Matsui N, Kaji R, Yasutomo K, Scientific Reports, 6:33692. 2016
  • Practical methods for collecting Trichinella parasites and their excretory-secretory products, Wu Z, Nagano I, Takahashi Y, Maekawa Y, Parasitology International, 65:591-595. 2016
  • Usefulness of miRNA profiles for predicting pathological responses to neoadjuvant chemotherapy in patients with human epidermal growth factor receptor 2-positive breast cancer, Ohzawa H, Miki A, Teratani T, Shiba S, Sakura Y, Nishimura W, Noda Y, Fukushima N, Fuji H, Hozumi Y, Mukai H, Yasuda Y, Oncol Lett 13: 1731-1740, 2017.
  • Design and Synthesis of Potent and Highly Selective Orexin 1 Receptor Antagonists with a Morphinan Skeleton and Their Pharmacologies, *Nagase H., N. Yamamoto, and M. Yanagisawa et al. , J. Med. Chem., 60, 1018-1040, 2017.
  • Moxd1 Is a Marker for Sexual Dimorphism in the Medial Preoptic Area, Bed Nucleus of the Stria Terminalis and Medial Amygdala. Tsuneoka Y. and *H. Funato et al. ,Front. Neuroanat. 11:26, 2017 doi:10.3389/fnana.2017.00026
  • Actin-binding protein coronin 1A controls osteoclastic bone resorption by regulating lysosomal secretion of cathepsin K, Ohmae S, Noma N, Toyomoto M, Shinohara M, Takeiri M, Fuji H, Takemoto K, Iwaisako K, Fujita T, Takeda N, Kawatani M, Aoyama M, Hagiwara M, Ishihama Y, Asagiri M, Sci Rep. doi:10.1038/srep41710, 2017
  • Mohawk transcription factor regulates homeostasis of the periodontal ligament. Koda N, Sato T, Shinohara M, Ichinose S, Ito Y, Nakamichi R, Kayama T, Kataoka K, Suzuki H, Moriyama K, Asahara HDevelopment, 144: 313-320, 2017
  • Prenatal myonuclei play a crucial role for skeletal muscle hypertrophy in rodents, Kawano F*, Ono Y*, Fujita R, Watanabe A, Masuzawa R, Shibata K, Hasegawa S, Nakata K, and Nakai N, Am. J. Physiol. Cell Physiol. 312: C233-C243, 2017. (*equally contributed authors)
  • Oral exposure to arsenic causes hearing loss in young people aged 12-29 years and in young mice, Li X, Ohgami N, Omata Y, Yajima I, Iida M, Oshino R, Ohnuma S, Ahsan N, Akhand AA, Kato M, Sci Rep., 2017
  • Arsenic-mediated hyperpigmentation in skin via NF-kappa B/endothelin-1 signaling in an originally developed hairless mouse model, Yajima I, Kumasaka MY, Iida M, Oshino R, Tanihata H, Al Hossain, Ohgami N, Kato M, Arch Toxicol., doi:10.1007/s00204-017-1975-0, 2017
  • Exposure to diphtheria toxin during the juvenile period impairs both inner and outer hair cells in C57BL/6 mice., Konishi H, Ohgami N, Matsushita A, Kondo Y, Aoyama Y, Kobayashi M, Nagai T, Ugawa S, Yamada K, Kato M, Kiyama H, Neuroscience, 2017 May 20;351:15-23. doi:10.1016/j.neuroscience.2017.03.028, 2017
  • Risk assessment of neonatal exposure to low frequency noise based on balance in mice, Ohgami N, Oshino R, Ninomiya H, Li X, Kato M, Yajima I, Kato M, Front Behav Neurosci., 11:30, doi:10.3389/fnbeh.2017.00030, (2017).
  • Arsenic levels in cutaneous appendicular organs are correlated with digitally evaluated hyperpigmented skin of the forehead but not the sole in Bangladesh residents, Yajima I, Ahsan N, Akhand AA, Al Hossain, Yoshinaga M, Ohgami N, Iida M, Oshino R, Naito M, Wakai K, Kato M, J Expo Sci Environ Epidemiol., doi: 10.1038/jes.2016.70, 2017.
  • Manganese-mediated acceleration of age-related hearing loss in mice. Kato M, Ohgami N, Yajima I, Iida M, Li X, Oshino R, Kumasaka MY, Sci Rep., 6: 36306, doi:10.1038/srep36306, 2016
  • Network dynamics mediate circadian clock plasticity, Azzi A, Evans JA, Leise T, Myung J, Takumi T, Davidson AJ, & Brown SA, Neuron. 93:441-450,2017
  • Moran's I quantifies spatio-temporal pattern formation in neural imaging data, Schmal C, Myung J, Herzel H, & Bordyugov G, Bioinformatics. doi:10.1093/bioinformatics/btx351, 2017

2016

  • Opioid System in the Lateral Hypothalamus Regulate Feeding Behavior Through Orexin and GABA Neurons, Ardianto C., N. Yonemochi, S. Yamamoto, L. Yang, F. Takenoya, S. Shioda, H. Nagase, *H. Ikeda, J. Kamei, Neuroscience, 320, 183-193, 2016.
  • Noisy galvanic vestibular stimulation induces a sustained improvement in body balance in elderly adults. Fujimoto C, Yamamoto Y, Kamogashira T, Kinoshita M, Egami N, Uemura Y, Togo F, Yamasoba T, *Iwasaki S, Scientific Reports, 6: 37575, doi:10.1038/srep37575, 2016
  • Novel roles of FKBP5 in muscle alteration induced by gravity change in mice, Shimode T, Kawao N, Tamura Y, Morita H, *Kaji H.Biochemical and Biophysical Research Communicationis, 479: 602-606, doi:10.1016/j.bbrc.2016.09.126, 2016
  • The vestibular system is critical for the changes in muscle and bone induced by hypergravity in mice, Kawao N, Morita H, Obata K, Tamura Y, Kaji H, Physiological Reports, 2016 Oct; 4(19): e12979.
  • Long-term exposure to microgravity impairs vestibulo-cardiovascular reflex, Morita H, Abe C, Tanaka K, 10.1038/srep33405, Scientific Reports, 2016
  • Non-encapsulated Trichinella pseudospiralis infection impairs follicular helper T cell differentiation with subclass-selective decreases in antibody responses, Asano T, Wu Z, Srinontong P, Ikeda I, Nagano I, Morita H, Maekawa Y, Infection and Immunity, 84:3550-3556. 2016
  • Peripherally administered orexin improves survival of mice with endotoxin shock, Ogawa Y, and *M. Yanagisawa et al. ,Elife. 2016 Dec 30;5. pii: e21055.
  • QRFP-Deficient Mice Are Hypophagic, Lean, Hypoactive and Exhibit Increased Anxiety-Like Behavior., Okamoto K, M. Yanagisawa, and *T. Sakurai et al. , PLoS One. 11: e0164716, 2016.
  • Forward-genetics analysis of sleep in randomly mutagenized mice. *Funato H. and *M. Yanagisawa et al. , Nature, 539, 378-383, 2016
  • Identification of mutations through dominant screening for obesity using C57BL/6 substrains, Scientific Reports, Scientific Reports 6, Article number: 32453, doi:10.1038/srep32453, 2016
  • Gene targeting of the transcription factor Mohawk in rats causes heterotropic ossification of Achilles tendon via failed tenogenesis, Suzuki H, Ito Y, Shinohara M, Yamashita S, Ichinose S, Kishida A, Oyaizu T, Kayama T, Nakamichi R, Koda N, Yagishita K, Lotz MK, Okawa A, Asahara H, Proc Natl Acad Sci USA, 113: 7840-7845, 2016
  • Ground-based assessment of JAXA mouse habitat cage unit by mouse phenotypic studies, Shimbo M, Kudo T, Hamada M, Jeon H, Imamura Y, Asano K, Okada R, Tsunakawa Y, Mizuno S, Yagami K, Ishikawa C, Li H, Shiga T, Ishida J, Hamada J, Murata K, Ishimaru T, Hashimoto M, Fukamizu A, Yamane M, Ikawa M, Morita H, Shinohara M, Asahara H, Akiyama T, Akiyama N, Sasanuma H, Yoshida N, Zhou R, Wang YY, Ito T, Kokubu Y, Noguchi TK, Ishimine H, Kurisaki A, Shiba D, Mizuno H, Shirakawa M, Ito N, Takeda S and Takahashi S. Exp Anim, 65: 175-187, 2016
  • Epidemiological analysis of the association between hearing and barium in humans, Ohgami N, Mitsumatsu Y, Ahsan N, Akhand AA, Li X, Iida M, Yajima I, Naito M, Wakai K, Ohnuma S, Kato M. J Expo Sci Environ Epidemiol., 26(5): 488-493, doi:10.1038/jes.2015.62, 2016
  • Manganese-mediated acceleration of age-related hearing loss in mice., Ohgami N, Yajima I, Iida M, Li X, Oshino R, Kumasaka MY, Kato M, Sci Rep. 8;6:36306. doi:10.1038/srep36306, 2016
  • The relationship between widespread changes in gravity and cerebral blood flow, Ogawa Y, Yanagida R, Ueda K, Aoki K, Iwasaki K, Environmental Health and Preventive Medicine, 21:186-192, July 2016
  • Mechanism of dendritic translation and localization of brain-derived neurotrophic factor, Oe S, Miki H, Nishimura W, Noda Y, Cell Struct Funct 41: 23-31, 2016

2015

  • Design and Synthesis of Non-Peptide, Selective Orexin Receptor 2 Agonists, Nagahara T., T. Saitoh, T. Kutsumura, N. Irukayama-Tomobe, Y. Ogawa, Y. Kuroda, D. Gouda, H. Kumagai, H. Fujii, M. Yanagisawa, *H. Nagase, J. Med. Chem., 58: 7931-7937, 2015.