A01 : Living body's dependence on gravity; the study of plasticity and collapse mechanisms - Publications

Original Articles

  1. 2017
  2. 2016
  3. 2015

2017

  • Antiangiogenic agent sunitinib induces epithelial to mesenchymal transition and accelerates motility of colorectal cancer cells, Tomida C, Yamagishi N, Nagano H, Uchida T, Ohno A, Hirasaka K, *Nikawa T, Teshima-Kondo S., J Med Invest. 2017;64(3.4):250-254. doi: 10.2152/jmi.64.250
  • Regorafenib induces adaptive resistance of colorectal cancer cells via inhibition of vascular endothelial growth factor receptor, Tomida C, Nagano H, Yamagishi N, Uchida T, Ohno A, Hirasaka K, *Nikawa T, Teshima-Kondo S, J Med Invest. 2017;64(3.4):262-265. doi: 10.2152/jmi.64.262.
  • Heat-induced calcium leakage causes mitochondrial damage in Caenorhabditis elegans body-wall muscles. , Momma K, Homma T, Isaka R, Sudevan S, Higashitani A. ,Genetics , Volume 206 Issue, August 2017, https://doi.org/10.1534/genetics.117.202747
  • Nutritional counseling effectively regulates inter-dialysis weight gain and blood pressure of maintenance hemodialysis outpatients. Sakai A, Hamada H, Hara K, Mori K, Mizuguchi T, Minaguchi J, Shima K, Kawashima S, Yamagata K, Okumura Y, Nikawa T. J Med Invest , Vol.64, 129-135pp, 2017
  • Altered KYN/TRP, Gln/Glu, and Met/methionine sulfoxide ratios in the blood plasma of medication-free patients with major depressive disorder, Hidehiro Umehara, Shusuke Numata, Shin-ya Watanabe, Yutaka Hatakeyama, Makoto Kinoshita, Yukiko Tomioka, Kiyoshi Nakahara, Takeshi Nikawa, Tetsuo Ohmori, Sci Rep,Scientific Reports 7, Article number: 4855, 2017, doi:10.1038/s41598-017-05121-6
  • Development and performance evaluation of a three-dimensional clinostat synchronized heavy-ion irradiation system. Ikeda H, Souda H, Puspitasari A, Held KD, Hidema J, Nikawa T, Yoshida Y, Kanai T, Takahashi A. Life Sci Space Res (Amst), 2017 Feb;12:51-60. doi:10.1016/j.lssr.2017.01.003. Epub 2017 Jan
  • Secretome analysis to elucidate metalloprotease-dependent ectodomain shedding of glycoproteins during neuronal differentiation. Tsumagari K, Shirakabe K, Ogura M, Sato F, Ishihama Y and Sehara-Fujisawa A., Gene to Cells, doi:10.1111/gtc.12466, 2017
  • YAP is essential for 3D organogenesis withstanding gravity. ,Asaoka Y, Nishina H, Furutani-Seiki M. Dev Growth Differ. 59: 52-58, doi: 10.1111/dgd.12338, 2017
  • Activation of the hypothalamic feeding centre upon visual prey detection, Akira Muto, Pradeep Lal, Deepak Ailani, Gembu Abe, Mari Itoh, Koichi Kawakami, Nature Communications 8, Article number: 15029, doi:10.1038/ncomms15029, 2017

2016

  • Fluid dynamics alter Caenorhabditis elegans body length via TGF-β/DBL-1 neuromuscular signaling., Harada S, Hashizume T, Nemoto K, Shao Z, Higashitani N, Etheridge T, Szewczyk NJ, Fukui K, Higashibata A and Higashitani A. , npj Microgravity, 2: 16006, doi:10.1038/npjmgrav.2016.6, 2016
  • Microgravity elicits reproducible alterations in cytoskeletal and metabolic gene and protein expression in space-flown Caenorhabditis elegans, Akira Higashibata, Toko Hashizume, Kanako Nemoto, Nahoko Higashitani, Timothy Etheridge, Chihiro Mori, Shunsuke Harada, Tomoko Sugimoto, Nathaniel J Szewczyk, Shoji A Baba, Yoshihiro Mogami, Keiji Fukui & Atsushi Higashitani, npj Microgravity, 2: 15022 , doi:10.1038/npjmgrav.2015.22, 2016
  • Modulation of cutaneous extracellular collagen contraction by phosphorylation status of p130Cas. Takeya M, Okumura Y, Nikawa T. J Physiol Sci, Volume 67, Issue 5, pp 613-622, 2017(First Online: 07 October 2016)
  • 8-Prenylnaringenin promotes recovery from immobilization-induced disuse muscle atrophy through activation of the Akt phosphorylation pathway in mice. Mukai R, Horikawa H, Lin PY, Tsukumo N, Nikawa T, Kawamura T, Nemoto H, Terao J. Am J Physiol Regul Integr Comp Physiol. 311(6):R1022-R1031.,2016
  • Dietary supplementation with isoflavones prevents muscle wasting in tumor-bearing mice. Hirasaka K, Saito S, Yamaguchi S, Miyazaki R, Wang Y, Haruna M, Taniyama S, Higashitani A, Terao J, Nikawa T, Tachibana K. J Nutr Sci Vitaminol (Tokyo). 62(3):178-84. 2016
  • Preventive effect of dietary quercetin on disuse muscle atrophy by targeting mitochondria in denervated mice. Mukai R, Matsui N, Fujikura Y, Matsumoto N, Hou DX, Kanzaki N, Shibata H, Horikawa M, Iwasa K, Hirasaka K, Nikawa T, Terao J. J Nutr Biochem. 31:67-76, 2016
  • Capric Acid Up-Regulates UCP3 Expression without PDK4 Induction in Mouse C2C12 Myotubes. Abe T, Hirasaka K, Kohno S, Tomida C, Haruna M, Uchida T, Ohno A, Oarada M, Teshima-Kondo S, Okumura Y, Choi I, Aoyama T, Terao J, Nikawa T. J Nutr Sci Vitaminol (Tokyo). 62(1):32-9, 2016
  • UCP3 is associated with Hax-1 in mitochondria in the presence of calcium ion. Hirasaka K, Mills EM, Haruna M, Bando A, Ikeda C, Abe T, Kohno S, Nowinski SM, Lago CU, Akagi K, Tochio H, Ohno A, Teshima-Kondo S, Okumura Y, Nikawa T. Biochem Biophys Res Commun. 472(1):108-13, 2016
  • TRPC3 positively regulates reactive oxygen species driving maladaptive cardiac remodeling, Kitajima N., Numaga-Tomita T., Watanabe M., Kuroda T., Nishimura A., Miyano K., Yasuda S., Kuwahara K., Sato Y., Ide T, Birnbaumer L., Sumimoto H., Mori Y. and Nishida M,Scientific Reports 6:37001. doi: 10.1038/srep37001 ,2016
  • TRPC3-GEF-H1 axis mediates pressure overload-induced cardiac fibrosis,Numaga-Tomita T., Kitajima N., Kuroda T., Nishimura A., Miyano K., Yasuda S., Kuwahara K., Sato Y., Ide T., Birnbaumer L., Sumimoto H., Mori Y. and Nishida M, Scientific Reports 6:39383. doi:10.1038/srep39383, 2016
  • Acute transcriptional up-regulation specific to osteoblasts/osteoclasts in medaka fish immediately after exposure to microgravity, Chatani M, Morimoto H, Takeyama K, Mantoku A, Tanigawa N, Kubota K, Suzuki H, Uchida S, Tanigaki F, Shirakawa M, Gusev O, Sychev V, Takano Y, Itoh T, Kudo A, Sci Rep. 6: 39545, 2016, 1-14, doi:10.1038/srep39545.
  • ADAM12-deficient zebrafish exhibit retardation in body growth at the juvenile stage without developmental defects. ,Tokumasu Y, Iida A, Wang Z, Ansai S, Kinoshita M, and Sehara-Fujisawa A. Development, Growth & Differentation, 58(4):409-421, doi:10.1111/dgd.12286, 2016
  • Visualization of Neuregulin 1 ectodomain shedding reveals its local processing in vitro and in vivo, Kamezaki A, Sato F, Aoki K, Asakawa K, Kawakami K, Matsuzaki F, Sehara-Fujisawa A. . Scientific Rep., 6:28873, doi:10.1038/srep28873, 2016
  • Optimization of a neurotoxin to investigate the contribution of excitatory interneurons to speed modulation in vivo. Sternberg, J.R., Severi, K.E., Fidelin, K., Gomez, J., Ihara, H., Alcheikh, Y., Hubbard, J. M., Kawakami, K., Suster, M., and Wyatt, C. Current Biology 17, 2319-2328, 2016
  • Ground-based assessment of JAXA mouse habitat cage unit by mouse phenotypic studies, Shimbo M, Kudo T, Hamada M, Jeon H, Imamura Y, Asano K, Okada R, Tsunakawa Y, Mizuno S, Yagami K, Ishikawa C, Li H, Shiga T, Ishida J, Hamada J, Murata K, Ishimaru T, Hashimoto M, Fukamizu A, Yamane M, Ikawa M, Morita H, Shinohara M, Asahara H, Akiyama T, Akiyama N, Sasanuma H, Yoshida N, Zhou R, Wang YY, Ito T, Kokubu Y, Noguchi TA, Ishimine H, Kurisaki A, Shiba D, Mizuno H, Shirakawa M, Ito N, Takeda S, Takahashi S, Experimental Animals. 65:175-187. doi: 0.1538/expanim.15-0077, 2016 (*本論文は掲載紙の表紙に選ばれた)
  • Identification of embryonic precursor cells that differentiate into thymic epithelial cells expressing autoimmune regulator, Nobuko Akiyama, Nobukazu Takizawa, Maki Miyauchi, Hiromi Yanai, Ryosuke Tateishi, Miho Shinzawa, Riko Yoshinaga, Masaaki Kurihara, Yosuke Demizu, Hisataka Yasuda, Shintaro Yagi, Guoying Wu, Mitsuru Matsumoto, Reiko Sakamoto, Nobuaki Yoshida, Josef M. Penninger, Yasuhiro Kobayashi, Jun‑ichiro Inoue, and Taishin Akiyama,, The Journal of Experimental Medicine, Vol. 213, No. 8, 1441–1458, Jul.11, 2016

2015

  • Molecular dynamics study on protein–water interplay in the mechanogating of the bacterial mechanosensitive channel MscL. , Sawada Y, Sokabe M, Eur J Biophys. 44 :531-43, doi:10.1007/s00249-015-1065-2. 2015
  • Unidirectional incorporation of a bacterial mechanosensitive channel into liposomal membranes, Nomura T, Cox CD, Bavi N, Sokabe M, Martinac B. FASEB J, 10: 4334-45, doi:10.1096/fj.15-275198.,2015
  • Ion Channels Activated by Mechanical Forces in Bacterial and Eukaryotic Cells. Subcell Biochem: High Pressure Bioscience - Basic Concepts, Sokabe M, Sawada Y, Kobayashi T., Applications and Frontiers. 72:613-26, doi:10.1007/978-94-017-9918-8_28. ,2015