Visualizing cell function dynamics in virtual outer space – Publicly Invited Research

  1. A01 Akiyama
  2. A01 Ochi
  3. A01 Chatani
  4. A01 Seiki
  5. A01 Nikawa
  6. A01 Kawakami
  7. A01 Tomita
  8. A01 Honda
  1. A02 Shinohara
  2. A02 Maekawa
  3. A02 Ohgami
  4. A02 Nishimura
  5. A02 Kawano
  6. A02 Iwase
  7. A02 Furuichi
  8. A02 Myung
  9. A02 Kitamura
  1. A03 Nakamura
  2. A03 Harada
  3. A03 Ide
  4. A03 Shirai
  5. A03 Kakinuma
  1. B01 Lazarus
  2. B01 Miwa
  3. B01 Kunieda
  4. B01 Shimada
  5. B01 Kitaya
  6. B01 Sawano
Research Subject Visualizing cell function dynamics in virtual outer space
Research Group Leader
Asako Sakaue-Sawano

The purpose of this research is to better understand the effect of gravity and cosmic radiation on the cellular homeostasis by employing Direct Visualization technology. We will assemble several devices, such as 3D-clinostat and miniature light microscopy, to develop novel experimental systems, where mammalian cells expressing a variety of fluorescent probes (e.g. Fucci, oxidative stress probe, autophagy probe, inflammation probe, metabolic probe) are time-lapse imaged while exposed to micro- and hyper-gravity or cosmic radiation. Our study will provide valuable suggestions about how the humankind can spend healthy life in real outer space.