Study for aging of C. elegans in space – Publicly Invited Research

  1. A01 Akiyama
  2. A01 Ochi
  3. A01 Chatani
  4. A01 Seiki
  5. A01 Nikawa
  6. A01 Kawakami
  7. A01 Tomita
  8. A01 Honda
  1. A02 Shinohara
  2. A02 Maekawa
  3. A02 Ohgami
  4. A02 Nishimura
  5. A02 Kawano
  6. A02 Iwase
  7. A02 Furuichi
  8. A02 Myung
  9. A02 Kitamura
  1. A03 Nakamura
  2. A03 Harada
  3. A03 Ide
  4. A03 Shirai
  5. A03 Kakinuma
  1. B01 Lazarus
  2. B01 Miwa
  3. B01 Kunieda
  4. B01 Shimada
  5. B01 Kitaya
  6. B01 Sawano
Research Subject Study for aging of C. elegans in space
Research Group Leader
Yoko Honda
  • Yoko Honda
    Research Fellow, Center for Advanced Biomedical Sciences, Research Institute for Science and Engineering, Waseda University)
    Website
    http://
Research Collaborator(s)
  • Shuji Honda
    Research Fellow, Center for Advanced Biomedical Sciences, Research Institute for Science and Engineering, Waseda University)

The mechanism of aging is not well known. The aging rate and lifespan are believed to be determined by responses to environmental conditions as well as genetic factors. Therefore, we will clarify whether the lifespan and aging rate of Caenorhabditis elegans differ on the ground and in space. If its lifespan in space is longer or shorter than that on the ground, we will investigate whether that is due to microgravity or space radiation. Further, we will explore novel longevity genes that are expressed after a specific period of time in space. We will also study how insulin signaling affects the lifespan and aging rate in space. Finding novel longevity genes could lead to the development of genomic drug discovery for intervention in aging and age-related diseases in humans.